Posted: December 30th, 2021
Compose a 3500 words assignment on oxaliplatin. Needs to be plagiarism free! This was developed following discovery of cisplatin in an attempt to reduce the problematic side effects of cisplatin. This is administered intravenously, and till date, no commercially viable orally active agent has been reported to be accepted for therapy3,4. Like cisplatin, oxaliplatin is also associated with quite a few dose-limiting adverse effects, which include myelosuppression along with others5. These are neurotoxic side effects that include sensory peripheral neuropathy which can be dose limiting. The other side effects include gastrointestinal disturbances and ototoxicity, while renal function may be normally monitored during therapy6. In this assignment contemporary literature will be reviewed to address the effects of oxaliplatin genotoxicity on human lymphocytes by using various cytogenetic techniques.
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